BDBM167469 US9073911, 18

SMILES: Cn1nc(cc1-c1ccccc1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1

InChI Key: InChIKey=YSQWLFOWWSJZFH-HXUWFJFHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167469   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167469 (US9073911, 18) Show SMILES Cn1nc(cc1-c1ccccc1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C21H22N4O2/c1-25-19(15-5-3-2-4-6-15)13-18(24-25)21(26)23-17-9-7-16(8-10-17)20-14-22-11-12-27-20/h2-10,13,20,22H,11-12,14H2,1H3,(H,23,26)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.70	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM167469 (US9073911, 18) Show SMILES Cn1nc(cc1-c1ccccc1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C21H22N4O2/c1-25-19(15-5-3-2-4-6-15)13-18(24-25)21(26)23-17-9-7-16(8-10-17)20-14-22-11-12-27-20/h2-10,13,20,22H,11-12,14H2,1H3,(H,23,26)/t20-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25.4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair