BDBM167898 3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]pyrazine (6p)

SMILES: C1CCN(CC1)c1ccc(cc1)-c1cnc2cccnc2n1

InChI Key: InChIKey=FHUORDMYZZSXQS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 167898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM167898 (3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...) Show SMILES C1CCN(CC1)c1ccc(cc1)-c1cnc2cccnc2n1 Show InChI InChI=1S/C18H18N4/c1-2-11-22(12-3-1)15-8-6-14(7-9-15)17-13-20-16-5-4-10-19-18(16)21-17/h4-10,13H,1-3,11-12H2	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	8.0	25
University of Karachi					Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...				Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM167898 (3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...) Show SMILES C1CCN(CC1)c1ccc(cc1)-c1cnc2cccnc2n1 Show InChI InChI=1S/C18H18N4/c1-2-11-22(12-3-1)15-8-6-14(7-9-15)17-13-20-16-5-4-10-19-18(16)21-17/h4-10,13H,1-3,11-12H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.75E+3	n/a	n/a	n/a	n/a	8.0	25
University of Karachi					Assay Description A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...				Chem Biol Drug Des 86: 1115-20 (2015) Article DOI: 10.1111/cbdd.12579 BindingDB Entry DOI: 10.7270/Q2445K79
					More data for this Ligand-Target Pair