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SMILES: Cc1n[nH]c2c[n+]([O-])c(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

InChI Key: InChIKey=RFHGUSOCWHDKIH-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16793   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM16793
PNG
(5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-yl}-3...)
Show SMILES Cc1n[nH]c2c[n+]([O-])c(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r|
Show InChI InChI=1S/C21H21N5O2/c1-14-19-9-21(26(27)12-20(19)25-24-14)16-8-18(11-23-10-16)28-13-17(22)7-15-5-3-2-4-6-15/h2-6,8-12,17H,7,13,22H2,1H3,(H,24,25)/t17-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 104n/an/an/an/a7.522



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem 15: 2441-52 (2007)


Article DOI: 10.1016/j.bmc.2007.01.010
BindingDB Entry DOI: 10.7270/Q26Q1VGQ
More data for this
Ligand-Target Pair