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BDBM168006 US9073926, 40

SMILES: CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(C)c1

InChI Key: InChIKey=IEWJUSIVLMUWOD-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168006   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168006
PNG
(US9073926, 40)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(C)c1
Show InChI InChI=1/C17H18N6O2/c1-10-5-6-18-17(25)14-7-11-3-4-13(21-15(11)23(10)14)16(24)20-12-8-19-22(2)9-12/h3-4,7-10H,5-6H2,1-2H3,(H,18,25)(H,20,24)
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MMDB

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PC cid
PC sid
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US Patent
n/an/a 0.780n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair