BDBM168038 US9073926, 72

SMILES: CCn1c(NC(=O)c2ccc3cc4C(=O)NC[C@@H](C)n4c3n2)nc2ccccc12

InChI Key: InChIKey=QKXWJSXDKHCSDT-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM168038 (US9073926, 72) Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)NC[C@@H](C)n4c3n2)nc2ccccc12 |r| Show InChI InChI=1S/C21H20N6O2/c1-3-26-16-7-5-4-6-14(16)24-21(26)25-19(28)15-9-8-13-10-17-20(29)22-11-12(2)27(17)18(13)23-15/h4-10,12H,3,11H2,1-2H3,(H,22,29)(H,24,25,28)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26.5	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9073926 (2015) BindingDB Entry DOI: 10.7270/Q2BP01J6
					More data for this Ligand-Target Pair