BDBM168326 US9675571, 15

SMILES: CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(CC#C)cc1)[C@H]1C[C@H]1C(O)=O

InChI Key: InChIKey=JRLAFCMTCPUKHX-DNQXCXABSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168326   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM168326 (US9675571, 15) Show SMILES CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Nc1ccc(CC#C)cc1)[C@H]1C[C@H]1C(O)=O |r| Show InChI InChI=1S/C28H35N3O3/c1-6-7-20-8-11-22(12-9-20)29-28(34)30-25-14-21(23-15-24(23)27(32)33)10-13-26(25)31(16-18(2)3)17-19(4)5/h1,8-14,18-19,23-24H,7,15-17H2,2-5H3,(H,32,33)(H2,29,30,34)/t23-,24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	541	n/a	n/a	n/a	25
SRMLSC US Patent					Assay Description Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...				US Patent US9675571 (2017) BindingDB Entry DOI: 10.7270/Q2BK19HD
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