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SMILES: [#6]\[#6](-[#6])=[#6]\C1([#6])[#7]-[#6](=O)-c2c(Cl)cc(-[#7]-c3ccncn3)c(=O)n12

InChI Key: InChIKey=KDEUFEMJUSWRRR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168343   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM168343
PNG
(US9669031, 192 8-chloro-3-methyl-3-(2-methylprop-1...)
Show SMILES [#6]\[#6](-[#6])=[#6]\C1([#6])[#7]-[#6](=O)-c2c(Cl)cc(-[#7]-c3ccncn3)c(=O)n12
Show InChI InChI=1S/C16H16ClN5O2/c1-9(2)7-16(3)21-14(23)13-10(17)6-11(15(24)22(13)16)20-12-4-5-18-8-19-12/h4-8H,1-3H3,(H,21,23)(H,18,19,20)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/a25



eFFECTOR THERAPEUTICS, INC.

US Patent


Assay Description
Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...

US Patent US9669031 (2017)


BindingDB Entry DOI: 10.7270/Q26Q1VDT
More data for this
Ligand-Target Pair