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SMILES: CCOC(=O)Nc1ccc(NC(=O)Nc2cc(ccc2N(CC(C)C)CC(C)C)[C@@H]2C[C@@H]2C(O)=O)cc1

InChI Key: InChIKey=DGUSQWGPFOIVDE-GOTSBHOMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168414   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM168414
PNG
(US9675571, 71)
Show SMILES CCOC(=O)Nc1ccc(NC(=O)Nc2cc(ccc2N(CC(C)C)CC(C)C)[C@@H]2C[C@@H]2C(O)=O)cc1 |r|
Show InChI InChI=1S/C28H38N4O5/c1-6-37-28(36)30-21-10-8-20(9-11-21)29-27(35)31-24-13-19(22-14-23(22)26(33)34)7-12-25(24)32(15-17(2)3)16-18(4)5/h7-13,17-18,22-23H,6,14-16H2,1-5H3,(H,30,36)(H,33,34)(H2,29,31,35)/t22-,23-/m0/s1
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US Patent
n/an/an/an/a 519n/an/an/a25



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US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...

US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair