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SMILES: Cc1ccc(NC(=O)Nc2cc(ccc2N(CCCC(F)(F)F)C2CCCCC2)[C@H]2C[C@H]2C(O)=O)cc1

InChI Key: InChIKey=ULESQAOZXMDMEP-DHIUTWEWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168419   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Indoleamine 2,3-dioxygenase 1


(Homo sapiens (Human))		BDBM168419
PNG
(US9675571, 73)
Show SMILES Cc1ccc(NC(=O)Nc2cc(ccc2N(CCCC(F)(F)F)C2CCCCC2)[C@H]2C[C@H]2C(O)=O)cc1 |r|
Show InChI InChI=1S/C28H34F3N3O3/c1-18-8-11-20(12-9-18)32-27(37)33-24-16-19(22-17-23(22)26(35)36)10-13-25(24)34(15-5-14-28(29,30)31)21-6-3-2-4-7-21/h8-13,16,21-23H,2-7,14-15,17H2,1H3,(H,35,36)(H2,32,33,37)/t22-,23-/m1/s1
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US Patent
n/an/an/an/a 527n/an/an/a25



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US Patent


Assay Description
Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...

US Patent US9675571 (2017)


BindingDB Entry DOI: 10.7270/Q2BK19HD
More data for this
Ligand-Target Pair