BDBM168474 US9675593, 35

SMILES: CCOc1ccc(c(C)c1)-n1cc(-c2cnn(C)c2)c2CCCCc2c1=O

InChI Key: InChIKey=JZYROBJXQYRBDJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 (Homo sapiens (Human))	BDBM168474 (US9675593, 35) Show SMILES CCOc1ccc(c(C)c1)-n1cc(-c2cnn(C)c2)c2CCCCc2c1=O Show InChI InChI=1S/C22H25N3O2/c1-4-27-17-9-10-21(15(2)11-17)25-14-20(16-12-23-24(3)13-16)18-7-5-6-8-19(18)22(25)26/h9-14H,4-8H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...				US Patent US9675593 (2017) BindingDB Entry DOI: 10.7270/Q2319T24
					More data for this Ligand-Target Pair