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SMILES: N[C@H](COc1cncc(c1)-c1cc2cnccc2s1)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=IPKHSYHXXAIZDD-SFHVURJKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16920   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM16920
PNG
(3-[(2S)-2-amino-3-[(5-{thieno[3,2-c]pyridin-2-yl}p...)
Show SMILES N[C@H](COc1cncc(c1)-c1cc2cnccc2s1)Cc1c[nH]c2ccccc12 |r|
Show InChI InChI=1S/C23H20N4OS/c24-18(7-15-12-27-21-4-2-1-3-20(15)21)14-28-19-8-16(11-26-13-19)23-9-17-10-25-6-5-22(17)29-23/h1-6,8-13,18,27H,7,14,24H2/t18-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 488n/an/an/an/a7.522



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 3424-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.005
BindingDB Entry DOI: 10.7270/Q2K072JJ
More data for this
Ligand-Target Pair