BindingDB logo
myBDB logout

null

SMILES: N[C@H](COc1cncc(c1)-c1ccc2[nH]c(=O)[nH]c2c1)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=CQGHCCOBBCOGTN-KRWDZBQOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16927   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM16927
PNG
(5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridi...)
Show SMILES N[C@H](COc1cncc(c1)-c1ccc2[nH]c(=O)[nH]c2c1)Cc1c[nH]c2ccccc12 |r|
Show InChI InChI=1S/C23H21N5O2/c24-17(7-16-11-26-20-4-2-1-3-19(16)20)13-30-18-8-15(10-25-12-18)14-5-6-21-22(9-14)28-23(29)27-21/h1-6,8-12,17,26H,7,13,24H2,(H2,27,28,29)/t17-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 147n/an/an/an/a7.522



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 3424-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.005
BindingDB Entry DOI: 10.7270/Q2K072JJ
More data for this
Ligand-Target Pair