BDBM170071 US9073940, 429

SMILES: FC1(F)CN(C1)C(=O)CCN1CCC[C@@H](C1)n1nc(C(=O)N2CCOCC2)c2CS(=O)(=O)c3ccccc3-c12

InChI Key: InChIKey=LBXKRIWHCRXGHJ-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-kinases (PI3K) (Homo sapiens (Human))	BDBM170071 (US9073940, 429) Show SMILES FC1(F)CN(C1)C(=O)CCN1CCC[C@@H](C1)n1nc(C(=O)N2CCOCC2)c2CS(=O)(=O)c3ccccc3-c12 |r| Show InChI InChI=1S/C26H31F2N5O5S/c27-26(28)16-32(17-26)22(34)7-9-30-8-3-4-18(14-30)33-24-19-5-1-2-6-21(19)39(36,37)15-20(24)23(29-33)25(35)31-10-12-38-13-11-31/h1-2,5-6,18H,3-4,7-17H2/t18-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
MERCK SERONO SA US Patent					Assay Description The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...				US Patent US9073940 (2015) BindingDB Entry DOI: 10.7270/Q2ZC81N2
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