BDBM170449 US9085531, 78
SMILES: CN1CC(c2cc3ccccc3s2)c2ccc(CN3CCOCC3)cc2C1
InChI Key: InChIKey=QMOZFCXYKWWVFV-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM170449 (US9085531, 78) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM170449 (US9085531, 78) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 12.6 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM170449 (US9085531, 78) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 35.4 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Albany Molecular Research, Inc.; Bristol-Myers Squibb Company US Patent | Assay Description In order to evaluate the relative affinity of the various compounds at the NE, DA and 5HT transporters, HEK293E cell lines were developed to express ... | US Patent US9085531 (2015) BindingDB Entry DOI: 10.7270/Q24X56JQ | |||||||||||
More data for this Ligand-Target Pair |