null

SMILES: Oc1ccc(cc1O)-c1cc(c(s1)-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1

InChI Key: InChIKey=FXKBZSGWQMZEJJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-synuclein (Homo sapiens (Human))	BDBM170554 (US9085549, 61) Show SMILES Oc1ccc(cc1O)-c1cc(c(s1)-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H16O6S/c23-15-4-1-11(7-18(15)26)14-10-21(12-2-5-16(24)19(27)8-12)29-22(14)13-3-6-17(25)20(28)9-13/h1-10,23-28H	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
PROTEOTECH INC US Patent					Assay Description The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (Homo sapiens (Human))	BDBM170554 (US9085549, 61) Show SMILES Oc1ccc(cc1O)-c1cc(c(s1)-c1ccc(O)c(O)c1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C22H16O6S/c23-15-4-1-11(7-18(15)26)14-10-21(12-2-5-16(24)19(27)8-12)29-22(14)13-3-6-17(25)20(28)9-13/h1-10,23-28H	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
PROTEOTECH INC US Patent					Assay Description The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...				US Patent US9085549 (2015) BindingDB Entry DOI: 10.7270/Q2WD3Z9K
					More data for this Ligand-Target Pair