BDBM171827 US9085572, 46

SMILES: O=C(Cc1ccccc1)NCc1ccnc(c1)-n1[nH]cc(-c2cccnc2)c1=O

InChI Key: InChIKey=YSIOFIYWFXTLFW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 171827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Von Hippel-Lindau disease tumor suppressor protein (VBC) (Homo sapiens (Human))	BDBM171827 (US9085572, 46) Show SMILES O=C(Cc1ccccc1)NCc1ccnc(c1)-n1[nH]cc(-c2cccnc2)c1=O Show InChI InChI=1S/C22H19N5O2/c28-21(12-16-5-2-1-3-6-16)25-13-17-8-10-24-20(11-17)27-22(29)19(15-26-27)18-7-4-9-23-14-18/h1-11,14-15,26H,12-13H2,(H,25,28)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	700	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...				US Patent US9085572 (2015) BindingDB Entry DOI: 10.7270/Q2H70DMQ
					More data for this Ligand-Target Pair