new BindingDB logo
myBDB logout

BDBM172564 US9675593, 612

SMILES: Cn1cc(cn1)-c1c[nH]c(=O)c2[nH]ccc12

InChI Key: InChIKey=UJVIDPVDMWHZGA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172564   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-1


(Homo sapiens (Human))
BDBM172564
PNG
(US9675593, 612)
Show SMILES Cn1cc(cn1)-c1c[nH]c(=O)c2[nH]ccc12
Show InChI InChI=1S/C11H10N4O/c1-15-6-7(4-14-15)9-5-13-11(16)10-8(9)2-3-12-10/h2-6,12H,1H3,(H,13,16)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<5.00E+4n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...


US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair