BDBM172686 US9090628, 346::US9090628, 348

SMILES: CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC1CN(C)C

InChI Key: InChIKey=YHKYKDYCSFGCNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172686   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172686 (US9090628, 346 | US9090628, 348) Show SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC1CN(C)C Show InChI InChI=1S/C24H33N7O/c1-16(2)31-24(25-17(3)27-31)21-15-29-11-12-32-22-13-18(8-9-20(22)23(29)26-21)30-10-6-7-19(30)14-28(4)5/h8-9,13,15-16,19H,6-7,10-12,14H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.445	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM172686 (US9090628, 346 | US9090628, 348) Show SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)N1CCCC1CN(C)C Show InChI InChI=1S/C24H33N7O/c1-16(2)31-24(25-17(3)27-31)21-15-29-11-12-32-22-13-18(8-9-20(22)23(29)26-21)30-10-6-7-19(30)14-28(4)5/h8-9,13,15-16,19H,6-7,10-12,14H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.288	n/a	n/a	n/a	n/a	7.5	n/a
GENENTECH, INC. US Patent					Assay Description PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...				US Patent US9090628 (2015) BindingDB Entry DOI: 10.7270/Q26Q1W0V
					More data for this Ligand-Target Pair