BDBM172729 US9096515, 33b -(R)-Isomer::US9296681, 33b-(R)-Isomer
SMILES: CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1
InChI Key: InChIKey=ZEFQZGJPKZZHJW-KRWDZBQOSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ... | US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros... | US Patent US9296681 (2016) BindingDB Entry DOI: 10.7270/Q22B8WW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros... | US Patent US9296681 (2016) BindingDB Entry DOI: 10.7270/Q22B8WW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ... | US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros... | US Patent US9296681 (2016) BindingDB Entry DOI: 10.7270/Q22B8WW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
REVIVA PHARMACEUTICALS, INC. US Patent | Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ... | US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK | |||||||||||
More data for this Ligand-Target Pair |