BDBM172795 US9096559, 26

SMILES: Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)C2CC2)cc1)-c1ccccc1

InChI Key: InChIKey=NAXDXJNQDIRWFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM172795 (US9096559, 26) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)C2CC2)cc1)-c1ccccc1 Show InChI InChI=1S/C24H23N3O2/c25-21-13-12-20(17-4-2-1-3-5-17)14-22(21)27-24(29)19-8-6-16(7-9-19)15-26-23(28)18-10-11-18/h1-9,12-14,18H,10-11,15,25H2,(H,26,28)(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Novel compounds were tested for their ability to inhibit histone deacetylase, subtype 1 (HDAC1) using an in vitro deacetylation assay. The enzyme sou...				US Patent US9096559 (2015) BindingDB Entry DOI: 10.7270/Q2K07317
					More data for this Ligand-Target Pair