BDBM173087 US9096589, 5,7-Dimethyl-2-[(E)-2-(1-methyl-4-thiazol-5-yl-1H-imidazol-2-yl)-vinyl]-imidazo[1,2-a]pyrimidine

SMILES: Cc1cc(C)n2cc(\C=C\c3nc(cn3C)-c3cncs3)nc2n1

InChI Key: InChIKey=FYEUHVMQYDAENI-SNAWJCMRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173087 (US9096589, 5,7-Dimethyl-2-[(E)-2-(1-methyl-4-thiaz...) Show SMILES Cc1cc(C)n2cc(\C=C\c3nc(cn3C)-c3cncs3)nc2n1 Show InChI InChI=1S/C17H16N6S/c1-11-6-12(2)23-8-13(20-17(23)19-11)4-5-16-21-14(9-22(16)3)15-7-18-10-24-15/h4-10H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair