BDBM173090 US9096589, 2-[(E)-2-(4-Furan-3-yl-1-methyl-1H-imidazol-2-yl)-vinyl]-5,7-dimethyl-imidazo[1,2-a]pyrimidine

SMILES: Cc1cc(C)n2cc(\C=C\c3nc(cn3C)-c3ccoc3)nc2n1

InChI Key: InChIKey=RLSQUACJBCMZAE-SNAWJCMRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173090 (US9096589, 2-[(E)-2-(4-Furan-3-yl-1-methyl-1H-imid...) Show SMILES Cc1cc(C)n2cc(\C=C\c3nc(cn3C)-c3ccoc3)nc2n1 Show InChI InChI=1S/C18H17N5O/c1-12-8-13(2)23-9-15(20-18(23)19-12)4-5-17-21-16(10-22(17)3)14-6-7-24-11-14/h4-11H,1-3H3/b5-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair