BDBM173120 US9096589, 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES: Cc1cccc2nc(CCc3nc(c[nH]3)-c3cccnc3)nn12

InChI Key: InChIKey=ARTCUHKKIKXBNB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173120 (US9096589, 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imidaz...) Show SMILES Cc1cccc2nc(CCc3nc(c[nH]3)-c3cccnc3)nn12 Show InChI InChI=1S/C17H16N6/c1-12-4-2-6-17-21-16(22-23(12)17)8-7-15-19-11-14(20-15)13-5-3-9-18-10-13/h2-6,9-11H,7-8H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173120 (US9096589, 5-Methyl-2-[2-(4-pyridin-3-yl-1H-imidaz...) Show SMILES Cc1cccc2nc(CCc3nc(c[nH]3)-c3cccnc3)nn12 Show InChI InChI=1S/C17H16N6/c1-12-4-2-6-17-21-16(22-23(12)17)8-7-15-19-11-14(20-15)13-5-3-9-18-10-13/h2-6,9-11H,7-8H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair