null

SMILES: CNCC[C@H](O)Cn1cc(nc1CCc1nc2cccc(C)n2n1)-c1cccs1

InChI Key: InChIKey=NKRVFTIJUKVMNB-INIZCTEOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173149 (US9096589, (S)-4-Methylamino-1-{2-[2-(5-methyl-[1,...) Show SMILES CNCC[C@H](O)Cn1cc(nc1CCc1nc2cccc(C)n2n1)-c1cccs1 Show InChI InChI=1S/C21H26N6OS/c1-15-5-3-7-21-24-19(25-27(15)21)8-9-20-23-17(18-6-4-12-29-18)14-26(20)13-16(28)10-11-22-2/h3-7,12,14,16,22,28H,8-11,13H2,1-2H3/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair