BDBM173160 US9096589, 8-Methoxy-2-{2-[4-(5-methyl-furan-2-yl)-1H-imidazol-2-yl]-ethyl}-[1,2,4]triazolo[1,5-a]pyridine

SMILES: COc1cccn2nc(CCc3nc(c[nH]3)-c3ccc(C)o3)nc12

InChI Key: InChIKey=PFTSVLKZDDOITF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173160 (US9096589, 8-Methoxy-2-{2-[4-(5-methyl-furan-2-yl)...) Show SMILES COc1cccn2nc(CCc3nc(c[nH]3)-c3ccc(C)o3)nc12 Show InChI InChI=1S/C17H17N5O2/c1-11-5-6-13(24-11)12-10-18-15(19-12)7-8-16-20-17-14(23-2)4-3-9-22(17)21-16/h3-6,9-10H,7-8H2,1-2H3,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair