BDBM173164 US9096589, 5-Methyl-2-[2-(1-propyl-4-pyridin-3-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES: CCCn1cc(nc1CCc1nc2cccc(C)n2n1)-c1cccnc1

InChI Key: InChIKey=PQTHIVLFHWQHFL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173164 (US9096589, 5-Methyl-2-[2-(1-propyl-4-pyridin-3-yl-...) Show SMILES CCCn1cc(nc1CCc1nc2cccc(C)n2n1)-c1cccnc1 Show InChI InChI=1S/C20H22N6/c1-3-12-25-14-17(16-7-5-11-21-13-16)22-19(25)10-9-18-23-20-8-4-6-15(2)26(20)24-18/h4-8,11,13-14H,3,9-10,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair