BDBM173187 US9096589, 2-[2-(4-Furan-3-yl-1-methyl-1H-imidazol-2-yl)-ethyl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine

SMILES: Cc1cnc(C)c2nc(CCc3nc(cn3C)-c3ccoc3)nn12

InChI Key: InChIKey=CPKGULOUTBZVIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173187   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173187 (US9096589, 2-[2-(4-Furan-3-yl-1-methyl-1H-imidazol...) Show SMILES Cc1cnc(C)c2nc(CCc3nc(cn3C)-c3ccoc3)nn12 Show InChI InChI=1S/C17H18N6O/c1-11-8-18-12(2)17-20-15(21-23(11)17)4-5-16-19-14(9-22(16)3)13-6-7-24-10-13/h6-10H,4-5H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
					More data for this Ligand-Target Pair