null

SMILES: CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(O)cc1

InChI Key: InChIKey=PHJSFCUVLUXHGK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173518 (1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(O)cc1 Show InChI InChI=1S/C23H17F3N2O3S/c1-32(30,31)20-12-8-18(9-13-20)28-22(16-2-6-17(7-3-16)23(24,25)26)14-21(27-28)15-4-10-19(29)11-5-15/h2-14,29H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM173518 (1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(O)cc1 Show InChI InChI=1S/C23H17F3N2O3S/c1-32(30,31)20-12-8-18(9-13-20)28-22(16-2-6-17(7-3-16)23(24,25)26)14-21(27-28)15-4-10-19(29)11-5-15/h2-14,29H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair