BDBM17394 1,2,4-Triazole Compound, 52::5-[(cyclohexylmethyl)sulfanyl]-N-(4-methoxyphenyl)-4H-1,2,4-triazol-3-amine

SMILES: COc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1

InChI Key: InChIKey=QRZAVCKGFCAJMY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17394 (1,2,4-Triazole Compound, 52 | 5-[(cyclohexylmethyl...) Show SMILES COc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1 Show InChI InChI=1S/C16H22N4OS/c1-21-14-9-7-13(8-10-14)17-15-18-16(20-19-15)22-11-12-5-3-2-4-6-12/h7-10,12H,2-6,11H2,1H3,(H2,17,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
					More data for this Ligand-Target Pair