BDBM17467 1,2,3-triazole analogue, 23::5-(3-bromophenyl)-1H-1,2,3-triazole

SMILES: Brc1cccc(c1)-c1c[nH]nn1

InChI Key: InChIKey=BKJXSQXZIOTRTP-UHFFFAOYSA-N

Data: 1 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 17467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	4	-11.3	n/a	n/a	n/a	n/a	n/a	7.5	22
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 48: 5644-7 (2005) Article DOI: 10.1021/jm050408c BindingDB Entry DOI: 10.7270/Q26M3537
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	6.5	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Mus musculus)	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Tryptophan 2,3-dioxygenase (Homo sapiens (Human))	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of human TDO transfected in mouse P815B clone 19 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM17467 (1,2,3-triazole analogue, 23 | 5-(3-bromophenyl)-1H...) Show SMILES Brc1cccc(c1)-c1c[nH]nn1 Show InChI InChI=1S/C8H6BrN3/c9-7-3-1-2-6(4-7)8-5-10-12-11-8/h1-5H,(H,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig Center for Cancer Research of the University of Lausanne Curated by ChEMBL					Assay Description Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysis				J Med Chem 55: 5270-90 (2012) Article DOI: 10.1021/jm300260v BindingDB Entry DOI: 10.7270/Q27H1KNW
					More data for this Ligand-Target Pair