BindingDB logo
myBDB logout

null

SMILES: Fc1ccc2CCN(C3CCN(CC3)c3ccc(nn3)-c3cnn(CCN4CCOCC4)c3)c2c1

InChI Key: InChIKey=ALJLGQQGERMMMV-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 174883   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA desaturase 1


(Rattus norvegicus (Rat))		BDBM174883
PNG
(US9102669, 71)
Show SMILES Fc1ccc2CCN(C3CCN(CC3)c3ccc(nn3)-c3cnn(CCN4CCOCC4)c3)c2c1
Show InChI InChI=1S/C26H32FN7O/c27-22-2-1-20-5-10-34(25(20)17-22)23-6-8-32(9-7-23)26-4-3-24(29-30-26)21-18-28-33(19-21)12-11-31-13-15-35-16-14-31/h1-4,17-19,23H,5-16H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 275n/an/an/an/an/a25



Janssen Pharmaceutica NV

US Patent


Assay Description
The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...

US Patent US9102669 (2015)


BindingDB Entry DOI: 10.7270/Q2BC3X9V
More data for this
Ligand-Target Pair