null
SMILES: Fc1ccc(CNc2ncc(Cc3c[nH]c4ncc(Cl)cc34)cn2)cc1F
InChI Key: InChIKey=CRQRKOANWFJXDQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM174908 (US9096593, P-2008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Plexxikon Inc. US Patent | Assay Description In one assay the biochemical activity IC50 values are determined with respect to inhibition of c-Kit kinase activity, where inhibition of phosphoryla... | US Patent US9096593 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM174908 (US9096593, P-2008) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.5 | 30 |
Plexxikon Inc. US Patent | Assay Description In one assay the biochemical activity IC50 values are determined with respect to inhibition of Fms kinase activity, where inhibition of phosphorylati... | US Patent US9096593 (2015) BindingDB Entry DOI: 10.7270/Q2PK0DXR | |||||||||||
More data for this Ligand-Target Pair |