BDBM175273 Trans-1,3-Difluoro-5-styrylbenzene (12)

SMILES: Fc1cc(F)cc(\C=C/c2ccccc2)c1

InChI Key: InChIKey=AAXFRBBYBHBSBR-SREVYHEPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Mus musculus (Mouse))	BDBM175273 (Trans-1,3-Difluoro-5-styrylbenzene (12)) Show SMILES Fc1cc(F)cc(\C=C/c2ccccc2)c1 Show InChI InChI=1S/C14H10F2/c15-13-8-12(9-14(16)10-13)7-6-11-4-2-1-3-5-11/h1-10H/b7-6-	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.94E+5	n/a	n/a	n/a	n/a	6.8	n/a
Indian Institute of Integrative Medicine					Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...				Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13
					More data for this Ligand-Target Pair