BDBM175323 (E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N'-(pyridin-2-ylmethylene) benzohydrazide (18)

SMILES: Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccccn1

InChI Key: InChIKey=IYFNHQGTODAYFT-ZMOGYAJESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175323   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM175323 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)N\N=C\c1ccccn1 Show InChI InChI=1S/C22H19N5O/c1-14-11-19-20(12-15(14)2)26-21(25-19)16-6-8-17(9-7-16)22(28)27-24-13-18-5-3-4-10-23-18/h3-13H,1-2H3,(H,25,26)(H,27,28)/b24-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+4	n/a	n/a	n/a	n/a	6.8	n/a
Universiti Teknologi MARA (UiTM)					Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ...				Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M
					More data for this Ligand-Target Pair