BDBM17553 2-[(2-{[2-(1-methylpyrrolidin-2-yl)ethyl]carbamoyl}benzene)sulfonamido]-5,6,7,8-tetrahydronaphthalene-1-carboxylic acid::Anthranilic Acid Sulfonamide, 23b

SMILES: CN1CCCC1CCNC(=O)c1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O

InChI Key: InChIKey=RTHIORZAORGWSC-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17553 (2-[(2-{[2-(1-methylpyrrolidin-2-yl)ethyl]carbamoyl...) Show SMILES CN1CCCC1CCNC(=O)c1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O Show InChI InChI=1S/C25H31N3O5S/c1-28-16-6-8-18(28)14-15-26-24(29)20-10-4-5-11-22(20)34(32,33)27-21-13-12-17-7-2-3-9-19(17)23(21)25(30)31/h4-5,10-13,18,27H,2-3,6-9,14-16H2,1H3,(H,26,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	25
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				J Med Chem 49: 3832-49 (2006) Article DOI: 10.1021/jm0601001 BindingDB Entry DOI: 10.7270/Q22V2DDZ
					More data for this Ligand-Target Pair