BDBM175539 US9120744, CDE-064

SMILES: COc1cc(cc(OC)c1O)C(=O)N(C)CCN(C)C(=O)c1cc(OC)c(O)c(OC)c1

InChI Key: InChIKey=OROSLRADDKTVLM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 175539   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor 1 (Homo sapiens (Human))	BDBM175539 (US9120744, CDE-064) Show SMILES COc1cc(cc(OC)c1O)C(=O)N(C)CCN(C)C(=O)c1cc(OC)c(O)c(OC)c1 Show InChI InChI=1S/C22H28N2O8/c1-23(21(27)13-9-15(29-3)19(25)16(10-13)30-4)7-8-24(2)22(28)14-11-17(31-5)20(26)18(12-14)32-6/h9-12,25-26H,7-8H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20E+6	n/a	n/a	n/a	n/a	7.8	23
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent					Assay Description To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in...				US Patent US9120744 (2015) BindingDB Entry DOI: 10.7270/Q2QF8RN8
					More data for this Ligand-Target Pair