BDBM17618 5,6-disubstituted anthranilic acid sulfonamide, 9j::6-[(2-bromo-4-fluorobenzene)sulfonamido]-3-(furan-3-yl)-2-methoxybenzoic acid

SMILES: COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1ccoc1

InChI Key: InChIKey=ZIVNAJURFUWIOI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17618 (5,6-disubstituted anthranilic acid sulfonamide, 9j...) Show SMILES COc1c(ccc(NS(=O)(=O)c2ccc(F)cc2Br)c1C(O)=O)-c1ccoc1 Show InChI InChI=1S/C18H13BrFNO6S/c1-26-17-12(10-6-7-27-9-10)3-4-14(16(17)18(22)23)21-28(24,25)15-5-2-11(20)8-13(15)19/h2-9,21H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 17: 2817-22 (2007) Article DOI: 10.1016/j.bmcl.2007.02.062 BindingDB Entry DOI: 10.7270/Q2PK0DD1
					More data for this Ligand-Target Pair