null

SMILES: Fc1ccc(Oc2ccc(cc2)-c2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1

InChI Key: InChIKey=SZJCDQOKMAOZNY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176467   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM176467 (US9120752, 10 | US9765029, 10) Show SMILES Fc1ccc(Oc2ccc(cc2)-c2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C29H23FN4O4S/c30-23-9-13-25(14-10-23)38-24-11-7-22(8-12-24)27-5-2-6-28(32-27)29(35)33-15-17-34(18-16-33)39(36,37)26-4-1-3-21(19-26)20-31/h1-14,19H,15-18H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...				US Patent US9765029 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CKS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM176467 (US9120752, 10 | US9765029, 10) Show SMILES Fc1ccc(Oc2ccc(cc2)-c2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C29H23FN4O4S/c30-23-9-13-25(14-10-23)38-24-11-7-22(8-12-24)27-5-2-6-28(32-27)29(35)33-15-17-34(18-16-33)39(36,37)26-4-1-3-21(19-26)20-31/h1-14,19H,15-18H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma, L.P. US Patent					Assay Description Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...				US Patent US9120752 (2015) BindingDB Entry DOI: 10.7270/Q2B56HHN
					More data for this Ligand-Target Pair