BDBM176491 US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoethoxy)benzyl)-4-chlorophenyl-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol

SMILES: CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCN)cc2)c1

InChI Key: InChIKey=GKQAPNVIOUQZDP-CRSSMBPESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM176491 (US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoeth...) Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCN)cc2)c1 |r| Show InChI InChI=1S/C21H26ClNO5S/c1-29-21-19(26)17(24)18(25)20(28-21)13-4-7-16(22)14(11-13)10-12-2-5-15(6-3-12)27-9-8-23/h2-7,11,17-21,24-26H,8-10,23H2,1H3/t17-,18-,19+,20+,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	7.3	n/a
Lexicon Pharmaceuticals, Inc. US Patent					Assay Description Human sodium/glucose co-transporter type 2 (SGLT2; accession number P31639; GI:400337) was cloned into pIRESpuro2 vector for mammalian expression (co...				US Patent US9688710 (2017) BindingDB Entry DOI: 10.7270/Q2154F7P
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM176491 (US9688710, 72 (2S,3R,4R,5S,6R)-2-(3-(4-(2-aminoeth...) Show SMILES CS[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCN)cc2)c1 |r| Show InChI InChI=1S/C21H26ClNO5S/c1-29-21-19(26)17(24)18(25)20(28-21)13-4-7-16(22)14(11-13)10-12-2-5-15(6-3-12)27-9-8-23/h2-7,11,17-21,24-26H,8-10,23H2,1H3/t17-,18-,19+,20+,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.3	n/a
Lexicon Pharmaceuticals, Inc. US Patent					Assay Description Human sodium/glucose co-transporter type 1 (SGLT1; accession number NP_000334; GI: 4507031) was cloned into pIRESpuro2 vector for mammalian expressio...				US Patent US9688710 (2017) BindingDB Entry DOI: 10.7270/Q2154F7P
					More data for this Ligand-Target Pair