BDBM176517 US9120752, 55::US9765029, 55

SMILES: Fc1ccc(Oc2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1

InChI Key: InChIKey=VFCGCZGPOPRKDB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 176517   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM176517 (US9120752, 55 | US9765029, 55) Show SMILES Fc1ccc(Oc2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C23H19FN4O4S/c24-18-7-9-19(10-8-18)32-22-6-2-5-21(26-22)23(29)27-11-13-28(14-12-27)33(30,31)20-4-1-3-17(15-20)16-25/h1-10,15H,11-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. US Patent					Assay Description The assay buffer was formulated by removing 120 mL from a 1 L bottle of fresh, sterile dH2O (Mediatech, Herndon, Va.) and adding 100 mL of 10×HBSS th...				US Patent US9765029 (2017) BindingDB Entry DOI: 10.7270/Q2FX7CKS
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM176517 (US9120752, 55 | US9765029, 55) Show SMILES Fc1ccc(Oc2cccc(n2)C(=O)N2CCN(CC2)S(=O)(=O)c2cccc(c2)C#N)cc1 Show InChI InChI=1S/C23H19FN4O4S/c24-18-7-9-19(10-8-18)32-22-6-2-5-21(26-22)23(29)27-11-13-28(14-12-27)33(30,31)20-4-1-3-17(15-20)16-25/h1-10,15H,11-14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a	n/a	37
Purdue Pharma, L.P. US Patent					Assay Description Cells were prepared by plating the recombinant HEK293 cells or other host cells expressing either recombinant or non-recombinant, native, Nav1.7 alph...				US Patent US9120752 (2015) BindingDB Entry DOI: 10.7270/Q2B56HHN
					More data for this Ligand-Target Pair