BDBM176582 US9120756, 130

SMILES: Cc1c(CNC(=O)Cc2cccc(F)c2)n(nc1C(F)(F)F)-c1cccc(Cl)c1

InChI Key: InChIKey=YNHVUIOJESEHFI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176582 (US9120756, 130) Show SMILES Cc1c(CNC(=O)Cc2cccc(F)c2)n(nc1C(F)(F)F)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H16ClF4N3O/c1-12-17(11-26-18(29)9-13-4-2-6-15(22)8-13)28(27-19(12)20(23,24)25)16-7-3-5-14(21)10-16/h2-8,10H,9,11H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	112	-9.86	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair