BDBM176763 US9675612, 9 2-(Cyclopropylmethyl)-N-(1H-indazol-5-yl)[1,3]thiazolo[5,4-d]pyrimidin-7-amine

SMILES: C(C1CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1

InChI Key: InChIKey=CNEUDEVUGXYSLX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 176763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-interacting serine/threonine-protein kinase 1 (T344D) (Homo sapiens (Human))	BDBM176763 (US9675612, 9 2-(Cyclopropylmethyl)-N-(1H-indazol-5...) Show SMILES C(C1CC1)c1nc2c(Nc3ccc4[nH]ncc4c3)ncnc2s1 Show InChI InChI=1S/C16H14N6S/c1-2-9(1)5-13-21-14-15(17-8-18-16(14)23-13)20-11-3-4-12-10(6-11)7-19-22-12/h3-4,6-9H,1-2,5H2,(H,19,22)(H,17,18,20)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	7.5	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description For the assay 50 nL of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...				US Patent US9675612 (2017) BindingDB Entry DOI: 10.7270/Q2RN3612
					More data for this Ligand-Target Pair