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SMILES: CCCC(=O)c1cnc2ccc(cc2c1Nc1ccc(CN(C)C)cc1)-c1cnc(nc1)C#N

InChI Key: InChIKey=DJTQJRQFEHEOOF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177173   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))		BDBM177173
PNG
(US9120749, 539)
Show SMILES CCCC(=O)c1cnc2ccc(cc2c1Nc1ccc(CN(C)C)cc1)-c1cnc(nc1)C#N
Show InChI InChI=1S/C27H26N6O/c1-4-5-25(34)23-16-29-24-11-8-19(20-14-30-26(13-28)31-15-20)12-22(24)27(23)32-21-9-6-18(7-10-21)17-33(2)3/h6-12,14-16H,4-5,17H2,1-3H3,(H,29,32)
PDB

KEGG

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 3.80n/an/an/an/a7.425



ONCOTHERAPY SCIENCE, INC.

US Patent


Assay Description
MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...

US Patent US9120749 (2015)


BindingDB Entry DOI: 10.7270/Q2FX7872
More data for this
Ligand-Target Pair