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SMILES: CN(C)CCc1cccc(Nc2c(cnc3ccc(cc23)-c2cc(F)c(O)c(Cl)c2)C(=O)C2CC2)c1

InChI Key: InChIKey=YKIWOPZLJKEOKV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 177327   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))		BDBM177327
PNG
(US9120749, 693)
Show SMILES CN(C)CCc1cccc(Nc2c(cnc3ccc(cc23)-c2cc(F)c(O)c(Cl)c2)C(=O)C2CC2)c1
Show InChI InChI=1S/C29H27ClFN3O2/c1-34(2)11-10-17-4-3-5-21(12-17)33-27-22-13-19(20-14-24(30)29(36)25(31)15-20)8-9-26(22)32-16-23(27)28(35)18-6-7-18/h3-5,8-9,12-16,18,36H,6-7,10-11H2,1-2H3,(H,32,33)
PDB

KEGG

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antibodypedia
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UniChem

Similars
US Patent
n/an/a 8.30n/an/an/an/a7.425



ONCOTHERAPY SCIENCE, INC.

US Patent


Assay Description
MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...

US Patent US9120749 (2015)


BindingDB Entry DOI: 10.7270/Q2FX7872
More data for this
Ligand-Target Pair