null
SMILES: CN(C)CCc1cccc(Nc2c(cnc3ccc(cc23)-c2cc(Cl)c(O)c(Cl)c2)C(C)=O)c1
InChI Key: InChIKey=BAUGBGZTQBXESN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Maternal embryonic leucine zipper kinase (Homo sapiens (Human)) | BDBM177363 (US9120749, 729) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.4 | 25 |
ONCOTHERAPY SCIENCE, INC. US Patent | Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ... | US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872 | |||||||||||
More data for this Ligand-Target Pair |