BDBM177693 US9120772, 2

SMILES: CN(C)C(=O)c1cccc(Nc2c(NC(C3CCSCC3)c3ccc(C)o3)c(=O)c2=O)c1O

InChI Key: InChIKey=IBEUBSDJSIGMBZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM177693 (US9120772, 2) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(C3CCSCC3)c3ccc(C)o3)c(=O)c2=O)c1O Show InChI InChI=1S/C24H27N3O5S/c1-13-7-8-17(32-13)18(14-9-11-33-12-10-14)26-20-19(22(29)23(20)30)25-16-6-4-5-15(21(16)28)24(31)27(2)3/h4-8,14,18,25-26,28H,9-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the beta -ar...				US Patent US9120772 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QHF
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM177693 (US9120772, 2) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(C3CCSCC3)c3ccc(C)o3)c(=O)c2=O)c1O Show InChI InChI=1S/C24H27N3O5S/c1-13-7-8-17(32-13)18(14-9-11-33-12-10-14)26-20-19(22(29)23(20)30)25-16-6-4-5-15(21(16)28)24(31)27(2)3/h4-8,14,18,25-26,28H,9-12H2,1-3H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the beta -ar...				US Patent US9120772 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QHF
					More data for this Ligand-Target Pair