BDBM17779 2-[(hydroxycarbamoyl)methyl]pentanedioic acid::CHEMBL65043::hydroxamate, 41

SMILES: ONC(=O)CC(CCC(O)=O)C(O)=O

InChI Key: InChIKey=PILHIJIJVLWKNF-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate Carboxypeptidase II (GCPII) (Homo sapiens (Human))	BDBM17779 (2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...) Show SMILES ONC(=O)CC(CCC(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO6/c9-5(8-14)3-4(7(12)13)1-2-6(10)11/h4,14H,1-3H2,(H,8,9)(H,10,11)(H,12,13)	PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	7.4	37
MGI Pharma					Assay Description GCPII activity in vitro is monitored through the hydrolysis [3H]NAAG to NAA and [3H]Glu. The radioactivity-based assay was miniaturized to a 96-well ...				J Med Chem 49: 2876-85 (2006) Article DOI: 10.1021/jm051019l BindingDB Entry DOI: 10.7270/Q28C9TJD
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase II (Homo sapiens (Human))	BDBM17779 (2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...) Show SMILES ONC(=O)CC(CCC(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO6/c9-5(8-14)3-4(7(12)13)1-2-6(10)11/h4,14H,1-3H2,(H,8,9)(H,10,11)(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	220	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Concentration of the compound required for the neuroprotective effect determined by inhibition of GCP II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair
Glutamate carboxypeptidase II (Homo sapiens (Human))	BDBM17779 (2-[(hydroxycarbamoyl)methyl]pentanedioic acid | CH...) Show SMILES ONC(=O)CC(CCC(O)=O)C(O)=O Show InChI InChI=1S/C7H11NO6/c9-5(8-14)3-4(7(12)13)1-2-6(10)11/h4,14H,1-3H2,(H,8,9)(H,10,11)(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of Glutamate carboxypeptidase II				Bioorg Med Chem Lett 13: 2097-100 (2003) BindingDB Entry DOI: 10.7270/Q2Z60NF2
					More data for this Ligand-Target Pair