BDBM177811 US9120791, Example 29::US9603854, 29

SMILES: Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc2CCCc2c1

InChI Key: InChIKey=QLMAKWVTWZMJNV-QNGWXLTQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177811 (US9120791, Example 29 | US9603854, 29) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc2CCCc2c1 Show InChI InChI=1S/C45H45ClN4O4/c46-34-12-18-39(44(52)49-28-33-7-2-1-6-32(33)25-37(49)29-47-20-22-54-23-21-47)40(26-34)43-27-41(42-10-3-4-19-48(42)43)45(53)50(35-14-16-38(51)17-15-35)36-13-11-30-8-5-9-31(30)24-36/h1-2,6-7,11-18,24,26-27,37,51H,3-5,8-10,19-23,25,28-29H2/t37-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177811 (US9120791, Example 29 | US9603854, 29) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc2CCCc2c1 Show InChI InChI=1S/C45H45ClN4O4/c46-34-12-18-39(44(52)49-28-33-7-2-1-6-32(33)25-37(49)29-47-20-22-54-23-21-47)40(26-34)43-27-41(42-10-3-4-19-48(42)43)45(53)50(35-14-16-38(51)17-15-35)36-13-11-30-8-5-9-31(30)24-36/h1-2,6-7,11-18,24,26-27,37,51H,3-5,8-10,19-23,25,28-29H2/t37-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair