null

SMILES: Cn1ncc2cc(ccc12)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1

InChI Key: InChIKey=DFFPSTDTLQMNOX-DHUJRADRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177820 (US9120791, Example 39 | US9603854, 39) Show SMILES Cn1ncc2cc(ccc12)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1 Show InChI InChI=1S/C46H46N6O6/c1-48-40-14-11-34(23-32(40)27-47-48)52(33-9-12-36(53)13-10-33)46(55)39-24-42(50-15-5-4-8-41(39)50)37-25-43-44(58-21-20-57-43)26-38(37)45(54)51-28-31-7-3-2-6-30(31)22-35(51)29-49-16-18-56-19-17-49/h2-3,6-7,9-14,23-27,35,53H,4-5,8,15-22,28-29H2,1H3/t35-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177820 (US9120791, Example 39 | US9603854, 39) Show SMILES Cn1ncc2cc(ccc12)N(C(=O)c1cc(-c2cc3OCCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc(O)cc1 Show InChI InChI=1S/C46H46N6O6/c1-48-40-14-11-34(23-32(40)27-47-48)52(33-9-12-36(53)13-10-33)46(55)39-24-42(50-15-5-4-8-41(39)50)37-25-43-44(58-21-20-57-43)26-38(37)45(54)51-28-31-7-3-2-6-30(31)22-35(51)29-49-16-18-56-19-17-49/h2-3,6-7,9-14,23-27,35,53H,4-5,8,15-22,28-29H2,1H3/t35-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair