BDBM177998 US9120807, 10
SMILES: C=Cc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1
InChI Key: InChIKey=STQYXQGAZSYWDR-UHFFFAOYSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A1 (Homo sapiens (Human)) | BDBM177998 (US9120807, 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 161 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (A3) (Homo sapiens (Human)) | BDBM177998 (US9120807, 10) | GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 747 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2b (Homo sapiens (Human)) | BDBM177998 (US9120807, 10) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 52.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A2a (Homo sapiens (Human)) | BDBM177998 (US9120807, 10) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd. US Patent | Assay Description The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique... | US Patent US9120807 (2015) BindingDB Entry DOI: 10.7270/Q2NG4PDH | |||||||||||
More data for this Ligand-Target Pair |